BDBM521911 N-[3-[3-(difluoromethoxy)-2- naphthyl]-1H-pyrazol-4- yl]pyrazolo[1,5-a]pyrimidine- 3-carboxamide::US11155557, Example 1

SMILES FC(F)Oc1cc2ccccc2cc1-c1n[nH]cc1NC(=O)c1cnn2cccnc12

InChI Key InChIKey=VWYUDOILCXXTFT-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 521911   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM521911(N-[3-[3-(difluoromethoxy)-2- naphthyl]-1H-pyrazol-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus expression system using LRRKtide as substrate incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed